HCID 22768929、化合物 → HCID 22768927、化合物
反応式
[CH3:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-])=O)[CH:9]=2)=[N:6][N:5]2[CH:17]=[N:18][N:19]=[C:4]2[CH:3]=1>[Pt]=O.C(O)C>[NH2:14][C:10]1[CH:9]=[C:8]([C:7]2[C:2]([CH3:1])=[CH:3][C:4]3[N:5]([CH:17]=[N:18][N:19]=3)[N:6]=2)[CH:13]=[CH:12][CH:11]=1参加物
4
実験手順
A mixture comprising 2.28 g. of 7-methyl-6-(m-nitrophenyl)-1,2,4-triazolo[4,3-b]pyridazine (prepared as described in Example 4), 100 ml. of ethyl alcohol and a catalytic amount of platinum oxide is shaken in a Parr shaker under 40 pounds of hydrogen pressure for 11/2 hours. The reaction mixture is filtered free of catalyst and the filtrate is concentrated to afford the product of the example as a yellow solid, m.p. 182°-186° C.
後処理
- filtrationThe reaction mixture is filtered free of catalyst
- concentrationthe filtrate is concentrated
- customto afford the product of the example as a yellow solid, m.p. 182°-186° C.
出典と根拠
- ORDレコード
- ord-4157ddd3ab7642d4ad9633cde00ea024
- 出典データセット
- uspto-grants-1978_09
- 特許番号
- US04117130
反応ノート
読み込み中…