反応式
[F:1][C:2]([F:16])([CH:8]([OH:15])[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:3](OCC)=[O:4].[NH2:17][NH2:18]>>[F:1][C:2]([F:16])([CH:8]([OH:15])[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:3]([NH:17][NH2:18])=[O:4]参加物
3
実験手順
α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoic acid, hydrazide (50) was prepared in the manner described in Example 10 on a 20 mmol scale using ethyl α,α-difluoro-β-hydroxy-3-(4-pyridinyl)-propanoate and hydrazine to yield 2.7 g (62%) of product. This product was used immediately in the manner described in Example 51, below.
出典と根拠
- ORDレコード
- ord-772d126ea75847e689202feda7164bc5
- 出典データセット
- uspto-grants-1995_01
- 特許番号
- US05378840
関連ノート
読み込み中…