Methylhydrazine → 6,7-Dihydro-6-methyl-7-oxo-4-phenylthieno[2,3-d]pyridazine
反応式
[C:1]([C:9]1[CH:13]=[CH:12][S:11][C:10]=1[C:14]([OH:16])=O)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:17][NH:18][NH2:19]>C(O)C>[CH3:17][N:18]1[C:14](=[O:16])[C:10]2[S:11][CH:12]=[CH:13][C:9]=2[C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[N:19]1参加物
4
実験手順
A solution of 31.2 g (0.134 mol) of 3-benzoyl-2-thiophenecarboxylic acid in 400 mL of ethanol was treated with 9.3 (0.2 mol) of methylhydrazine at room temperature for 18 hours, refluxed 3 hours, cooled and 30.7 g of the product filtered off, mp 174-175.
後処理
- temperaturerefluxed 3 hours
- temperaturecooled
- filtration30.7 g of the product filtered off
出典と根拠
- ORDレコード
- ord-d3d95ea34d1840d7859ce02d6e194aea
- 出典データセット
- uspto-grants-1995_01
- 特許番号
- US05380721
反応ノート
読み込み中…