Ammonia → 2-Nitrophenyl phenyl ether

HRID 1769828

反応式

HRID 1769828 の反応式
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[C:11]1([O-:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[Na+].N>>[CH:14]1[CH:15]=[CH:16][C:11]([O:17][C:2]2[C:3]([N+:8]([O-:10])=[O:9])=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:12][CH:13]=1

参加物

4

反応物 3

HCID 222AmmoniaHCID 69451-Chloro-2-nitrobenzeneHCID 4445035Phenolate Sodium

生成物 1

HCID 166612-Nitrophenyl phenyl ether収率 93.9%

実験手順

A steel autoclave was filled with 157.6 g of o-chloronitrobenzene and 116.1 g of sodium phenolate. At room temperature, 150 g of liquid ammonia were pumped into the vessel, the mixture was heated to 600 with stirring for 15 hours and subsequently cooled. Removal of the ammonia by distillation and workup of the distillation residue gave 202 g of 2-nitrodiphenyl ether (94% of the theoretical yield), 98.5% pure.

後処理

  1. customAt room temperature
  2. temperaturethe mixture was heated to 600
  3. temperaturesubsequently cooled
  4. customRemoval of the ammonia
  5. distillationby distillation and workup of the distillation residue

出典と根拠

ORDレコード
ord-26fcceed456e444982cc43b30c71f271
出典データセット
uspto-grants-1995_01
特許番号
US05382686

関連ノート

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