Ethanol → Ethoxycarbonylpropyleneurea
反応式
[O:1]([C:8]([CH2:10][CH:11]([NH:13][C:14]([NH2:16])=[O:15])[CH3:12])=[O:9])[C:2]1C=CC=C[CH:3]=1.C(O)C.C([O-])(=O)CCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCC.C([Sn+2]CCCC)CCC>O1CCOCC1>[CH2:2]([O:1][C:8]([CH2:10][CH:11]([NH:13][C:14]([NH2:16])=[O:15])[CH3:12])=[O:9])[CH3:3]参加物
5
実験手順
Phenoxycarbonylpropyleneurea of 1 g (4.5 mmol) and ethanol of 10 g (21.7 mmol) were dissolved in dioxane of 20 ml by heating. Dibutyltin dilaurate of 10 mg (1%) was added to the resulting solution and the resulting mixture was heated for 5 hours with stirring. After confirming the completion of the reaction by the thin layer chromatography, the reaction product was concentrated and the resulting crude crystals were washed with ether to obtain the aimed substance of 567 mg (80%).
後処理
- temperatureby heating
- temperaturethe resulting mixture was heated for 5 hours
- customthe completion of the reaction by the thin layer chromatography
- concentrationthe reaction product was concentrated
- washthe resulting crude crystals were washed with ether
- customto obtain the aimed substance of 567 mg (80%)
出典と根拠
- ORDレコード
- ord-158e7b3fdb944bb99035cafc6a3d4f05
- 出典データセット
- uspto-grants-1995_01
- 特許番号
- US05385985
反応ノート
読み込み中…