化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Alcohol → Benzyl 8-bromooctanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Alcohol | HCID 244 | — |
| 反応物 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 反応物 | 8-Bromooctanoic acid | HCID 548275 | — |
| 触媒 | 4-Pyrrolidinopyridine | HCID 75567 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Benzyl 8-bromooctanoate | HCID 11278409 | 100.2% |
反応手順
This compound was prepared from 8-bromooctanoic acid (2.23 g; 10.0 mmol), benzyl alcohol (1.19 g; 11.0 mmol), N,N′-dicyclohexylcarbodiimide (DCC, 2.27 g; 11.0 mmol), and 4-pyrrolidinylpyridine (50 mg) in dry dichloromethane (50 mL) using Procedure A. 3.14 g (100%) product was obtained (clear oil that eventually solidified on standing).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09249086B2 |
| 出典データセット | uspto-grants-2016_02 |
| ORD ID | ord-1387cc3a850741b1bace81194970ff9f |
| 出典メモ | uspto-grants-2016_02 |