化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 7-Carboxyheptyl 5-amino-4-oxopentanoate hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 7-(benzyloxycarbonyl)heptyl 5-(Cbz-amino)-4-oxopentanoate | HCID 90034499 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 7-Carboxyheptyl 5-amino-4-oxopentanoate hydrochloride | HCID 90034497 | 70% |
反応手順
This compound was prepared from the product of 10b (0.70 g; 1.4 mmol), 12 M HCl (0.12 mL; 1.4 mmol), 10% Pd/C (100 mg), hydrogen gas, and 2-propanol (25 mL) using the procedure in Example 8d. 0.30 g (70%) product was obtained (white solid).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09249086B2 |
| 出典データセット | uspto-grants-2016_02 |
| ORD ID | ord-887101cd9ad64a7a8858326e84974336 |
| 出典メモ | uspto-grants-2016_02 |