Glyoxal, phenyl-, hydrate → 3-(Methylthio)-5-phenyl-1,2,4-triazine

反応式

[NH:1]([C:3]([S:5][CH3:6])=[NH:4])[NH2:2].O.[C:8]1([C:14]([CH:16]=O)=O)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH3:6][S:5][C:3]1[N:1]=[N:2][CH:16]=[C:14]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:4]=1

参加物

反応物 2

HCID 12215922Glyoxal, phenyl-, hydrate

HCID 178504051Methyl hydrazinecarbimidothioate

生成物 1

HCID 985413-(Methylthio)-5-phenyl-1,2,4-triazine収率 73.2%

実験手順

3-(Methylsulfanyl)-5-phenyl-1,2,4-triazine (2.93 g, 73%) was prepared from methyl hydrazinecarbimidothioate (2.07 g, 19.7 mmol) and phenylglyoxal monohydrate (2.89 g, 19.7 mmol) according to the general procedure of Preparation 2.

後処理

customaccording to the general procedure of Preparation 2

出典と根拠

ORDレコード: ord-1f4678adfd4845d08fa001dbeb60a397
出典データセット: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09249130B2

反応ノート

読み込み中…