Oxalic Acid → 4-(1-methylpiperidin-4-yloxy)-2-vinyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene oxalate

HRID 1773864ノート

反応式

HRID 1773864 の反応式
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([O:8][CH:9]2[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[CH2:16][CH2:15][N:14]3[C:10]2=[N:11][C:12]([CH:23]=[CH2:24])=[CH:13]3)[CH2:4][CH2:3]1.[C:25]([OH:30])(=[O:29])[C:26]([OH:28])=[O:27]>CC(C)=O>[C:25]([OH:30])(=[O:29])[C:26]([OH:28])=[O:27].[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([O:8][CH:9]2[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[CH2:16][CH2:15][N:14]3[C:10]2=[N:11][C:12]([CH:23]=[CH2:24])=[CH:13]3)[CH2:4][CH2:3]1

参加物

4

反応物 2

HCID 971Oxalic AcidHCID 867039504-(1-methylpiperidin-4-yloxy)-2-vinyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene

生成物 1

HCID 867039514-(1-methylpiperidin-4-yloxy)-2-vinyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene oxalate

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

4-(1-methylpiperidin-4-yloxy)-2-vinyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene is dissolved in acetone (1.7 mL) and oxalic acid (1 equivalent) is added. Acetone is removed under reduced pressure to afford 4-(1-methylpiperidin-4-yloxy)-2-vinyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene oxalate.

後処理

  1. customAcetone is removed under reduced pressure

出典と根拠

ORDレコード
ord-696ef5aa3b3c483a9c5329c55da0eed2
出典データセット
uspto-grants-2016_02
特許番号
US09255101B2

反応ノート

読み込み中…