Oxalic Acid → 2-(2-methyl-allyl)-4-(1-methylpiperidin-4-yloxy)-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene oxalate
反応式
[CH3:1][C:2](=[CH2:26])[CH2:3][C:4]1[N:13]=[C:12]2[N:6]([CH2:7][CH2:8][C:9]3[CH:25]=[CH:24][CH:23]=[CH:22][C:10]=3[CH:11]2[O:14][CH:15]2[CH2:20][CH2:19][N:18]([CH3:21])[CH2:17][CH2:16]2)[CH:5]=1.[C:27]([OH:32])(=[O:31])[C:28]([OH:30])=[O:29]>CC(C)=O>[C:27]([OH:32])(=[O:31])[C:28]([OH:30])=[O:29].[CH3:26][C:2](=[CH2:1])[CH2:3][C:4]1[N:13]=[C:12]2[N:6]([CH2:7][CH2:8][C:9]3[CH:25]=[CH:24][CH:23]=[CH:22][C:10]=3[CH:11]2[O:14][CH:15]2[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]2)[CH:5]=1参加物
4
実験手順
2-(2-methyl-allyl)-4-(1-methylpiperidin-4-yloxy)-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulene is dissolved in acetone (0.7 mL) and oxalic acid (1 equivalent) is added. Acetone is removed under reduced pressure to afford the product as an oxalate.