Pivaloyl chloride → HCID 136242919、化合物
反応式
O=C1C2C3C(C(OC)=O)=CC=CC=3NC=2CNC1.[C:19](Cl)(=[O:24])[C:20]([CH3:23])([CH3:22])[CH3:21].C1(C([N:31]2[CH2:43][C:42]3[NH:41][C:40]4[CH:39]=[CH:38][CH:37]=[C:36]5[C:44](=[O:47])[NH:45][N:46]=[C:33]([C:34]=3[C:35]=45)[CH2:32]2)=O)CC1>>[C:19]([N:31]1[CH2:43][C:42]2[NH:41][C:40]3[CH:39]=[CH:38][CH:37]=[C:36]4[C:44](=[O:47])[NH:45][N:46]=[C:33]([C:34]=2[C:35]=34)[CH2:32]1)(=[O:24])[C:20]([CH3:23])([CH3:22])[CH3:21]参加物
4
実験手順
Compound 51 was prepared from methyl 4-oxo-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-5-carboxylate and pivaloyl chloride according to the procedures similar to those for Compound 47. 1H NMR (DMSO-d6) δ 9.63 (s, 1H), 7.27-7.47 (m, 2H), 6.96 (s, 1H), 4.89 (s, 2H), 4.33 (s, 2H), and 1.24 (s, 9H). MS (ESI) m/e [M+1]+ 311.
出典と根拠
- ORDレコード
- ord-8bee0f0cff54472ca6ced82634e32729
- 出典データセット
- uspto-grants-2016_02
- DOI