Propanal → HCID 136242924、化合物
反応式
O=[C:2]1C2C3C(C(OC)=O)=CC=CC=3NC=2CN[CH2:3]1.C(=O)CC.[CH3:23][N:24]1[CH2:36][C:35]2[NH:34][C:33]3[CH:32]=[CH:31][CH:30]=[C:29]4[C:37](=[O:40])[NH:38][N:39]=[C:26]([C:27]=2[C:28]=34)[CH2:25]1>>[CH2:23]([N:24]1[CH2:36][C:35]2[NH:34][C:33]3[CH:32]=[CH:31][CH:30]=[C:29]4[C:37](=[O:40])[NH:38][N:39]=[C:26]([C:27]=2[C:28]=34)[CH2:25]1)[CH2:2][CH3:3]参加物
4
実験手順
Compound 56 was prepared from methyl 4-oxo-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-5-carboxylate and propionaldehyde according to the procedures similar to those for Compound 44. 1H NMR (DMSO-d6) δ 11.7 (s, 1H), 9.92 (s, 1H), 7.47 (d, 1H, J=7.8 Hz), 7.43 (d, 1H, J=7.8 Hz), 7.13 (t, 1H, J=7.8 Hz), 3.81 (s, 2H), 3.28 (s, 2H), 2.50-2.55 (m, 2H), 1.51-1.54 (m, 2H), and 0.89 (t, 3H, J=7.8 Hz). MS (ESI) m/e [M+1]+ 269.
出典と根拠
- ORDレコード
- ord-e5182b11298d461e88c97820653253f7
- 出典データセット
- uspto-grants-2016_02