化工社化工社 化学情報印刷レポート · 研究参考用
1,1'-Carbonyldiimidazole → hexahydroimidazo[1,5-a]pyridin-3(2H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 反応物 | Piperidine-2-methylamine | HCID 90865 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | hexahydroimidazo[1,5-a]pyridin-3(2H)-one | HCID 47002315 | — |
反応手順
A solution of CDI (830 mg, 5.1 mmol) and piperidin-2-ylmethanamine (520 mg, 4.6 mmol) in DCM (20 mL) was stirred at room temperature overnight. After the solvent was removed, the residue was directly used for the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09260452B2 |
| 出典データセット | uspto-grants-2016_02 |
| ORD ID | ord-619ee6518b044e9c8f2128490bba4c10 |
| 出典メモ | uspto-grants-2016_02 |