N-(3-mercaptophenyl)methanesulfonamide → (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido) phenylthio)carbonyloxy)ethyl)pyridine 1-oxide

反応式

[SH:1][C:2]1[CH:3]=[C:4]([NH:8][S:9]([CH3:12])(=[O:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.[Cl:13][C:14]1[CH:15]=[N+:16]([O-:51])[CH:17]=[C:18]([Cl:50])[C:19]=1[CH2:20][C@@H:21]([C:35]1[CH:40]=[CH:39][C:38]([O:41][CH:42]([F:44])[F:43])=[C:37]([O:45][CH2:46][CH:47]2[CH2:49][CH2:48]2)[CH:36]=1)[O:22][C:23](OC1C=CC([N+]([O-])=O)=CC=1)=[O:24]>C(Cl)Cl.CN(C1C=CN=CC=1)C>[Cl:50][C:18]1[CH:17]=[N+:16]([O-:51])[CH:15]=[C:14]([Cl:13])[C:19]=1[CH2:20][C@@H:21]([C:35]1[CH:40]=[CH:39][C:38]([O:41][CH:42]([F:44])[F:43])=[C:37]([O:45][CH2:46][CH:47]2[CH2:49][CH2:48]2)[CH:36]=1)[O:22][C:23]([S:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([NH:8][S:9]([CH3:12])(=[O:10])=[O:11])[CH:3]=1)=[O:24]