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Aldoxime → HCID 178466047、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Aldoxime | HCID 7863 | — |
| 反応物 | HCID 178507366 | HCID 178507366 | — |
| 反応物 | 2H-Benzotriazole-4-carbaldehyde | HCID 178519449 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 178466047 | HCID 178466047 | — |
反応手順
The ketone was prepared in the same manner as the benzotriazole aldehyde from 5-aminobenzotriazole and acetaldoxime. Column chromatography of the crude ketone using DCM and eluting with MeOH (0-10%) afforded the ketone in 11% yield. Rf [A] 0.3; δH(400 MHz; Acetone-d6) 2.68 (3H, s, CH3), 7.92 (1H, d, J 8.7, Ar—H), 8.07 (1H, d, 3 8.7 Ar—H), 8.62 (1H, s, Ar—H); m/z (FAB−HR) 162.06674 [(M+H)+ calc. for C8H8N3O 162.06682]. The hydrazone of the ketone was prepared from 2,4DNPH to afford an orange solid. 4,6-Dinitro-7-1H-benzotriazole [26]
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741102B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b0801a99f04f4e83a219a0e7897fc984 |
| 出典メモ | uspto-grants-2010_06 |