Acetic Anhydride → HCID 11041076、化合物

HRID 1779707ノート

反応式

HRID 1779707 の反応式
[CH3:1][CH:2]([C:7](=[O:13])[CH2:8][CH2:9][C:10]([CH3:12])=[CH2:11])[CH2:3][C:4]([OH:6])=O.C(OC(=O)C)(=O)C>>[CH3:1][C:2]1[CH:7]([CH2:8][CH:9]=[C:10]([CH3:11])[CH3:12])[O:13][C:4](=[O:6])[CH:3]=1

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 110195357-Octenoic acid, 3,7-dimethyl-4-oxo-

生成物 1

HCID 11041076HCID 11041076、化合物

実験手順

The thus-obtained 3,7-dimethyl-4-oxo-7-octenoic acid is then dissolved in a solvent and an equivalent amount or a somewhat excessive amount of acetic anhydride is added thereto and heated under reflux in the presence of an acid catalyst, whereby the acid is cyclized and dehydrated along with isomerization of the terminal double bond to give 3,7-dimethyl-2,6-octadien-4-olide. As the solvent in this process, usable is a hydrocarbon solvent such as pentane, hexane, heptane, benzene, toluene, xylene or the like. Especially preferred is toluene. As the acid catalyst, usable is an organic acid such as acetic acid, para-toluene-sulfonic acid, camphor-sulfonic acid or the like.

後処理

  1. temperatureheated
  2. temperatureunder reflux in the presence of an acid catalyst, whereby the acid

出典と根拠

ORDレコード
ord-252282c9a713493783db2779cb37c19f
出典データセット
uspto-grants-1997_05
特許番号
US05627288

反応ノート

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