ホームMCPワークベンチSkills
ホームワークベンチ通知マイページ
llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
  1. ホーム
  2. /反応

Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → HCID 67592430、化合物

HRID 1779990
ノート
印刷プレビュー

反応式

HRID 1779990 の反応式
[CH2:1]([CH:3]1[NH:7][C:6](=O)[CH2:5][CH:4]1[CH3:9])C.F[B-](F)(F)F.[CH3:15][O+:16]([CH3:18])C>C(Cl)Cl>[NH:7]([CH:3]1[CH:1]=[C:15]([O:16][CH3:18])[CH2:5][CH:4]1[CH3:9])[CH3:6]
参加物実験手順後処理出典と根拠反応ノート

参加物

4

反応物 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 184286185-Ethyl-4-methyl-2-pyrrolidinone

生成物 1

HCID 67592430HCID 67592430、化合物収率 79.3%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of 0.254 g (2 mmol) of 5-ethyl-4-methyl-2-pyrrolidone (from step B) in 3 mL of CH2Cl2 was added 0.355 g (2.4 mmol) of trimethyloxonium tetrafluoroborate under a N2 atmosphere. After stirring overnight the reaction mixture was quenched with saturated K2CO3 solution and diluted with Et2O. The solution was filtered and the filtrate was concentrated. The residue was purified by flash chromatography using Et2O-hexane to isolate 0.224 g (79%) of the title compound.

後処理

  1. customwas quenched with saturated K2CO3 solution
  2. additiondiluted with Et2O
  3. filtrationThe solution was filtered
  4. concentrationthe filtrate was concentrated
  5. customThe residue was purified by flash chromatography

出典と根拠

ORDレコード
ord-f48a6e7dc22546ea8439a5549e0809a6
出典データセット
uspto-grants-1997_05
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US05629322

反応ノート

読み込み中…

このページの内容参加物実験手順後処理出典と根拠反応ノート