Potassium Carbonate → HCID 54349857、化合物

HRID 1780005ノート

反応式

HRID 1780005 の反応式
[CH3:1][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:10])[C:3]([CH2:5][O:6]C(=O)C)=[O:4].C(=O)([O-])[O-].[K+].[K+]>CO>[CH3:10][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:1])[C:3]([CH2:5][OH:6])=[O:4]

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 53897658HCID 53897658、化合物

生成物 1

HCID 54349857HCID 54349857、化合物収率 98%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

N-(1',1'-dimethyl-3'-acetoxyacetonyl)-3,5-dichlorobenzamide (5.0 gm, 0.15 m) was treated with potassium carbonate (0.21 gm, 0.0015 m) in 250 ml methanol at room temperature for 12 hours. The methanol was removed by a vacuum, the residue was taken up in ether and washed successively with saturated sodium bicarbonate, water and brine. Drying of the ether solution followed by removing the solvent yielded 4.0 gm (98%) of pure product.

後処理

  1. customThe methanol was removed by a vacuum
  2. washwashed successively with saturated sodium bicarbonate, water and brine
  3. dry with materialDrying of the ether solution
  4. customby removing the solvent

出典と根拠

ORDレコード
ord-007253616b184568b6a3b6c3cad2d9d0
出典データセット
uspto-grants-1997_05
特許番号
US05629346

反応ノート

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