Acetone → Benzene, 1,2,5-trimethyl-3-[(2-methyl-2-propenyl)oxy]-

HRID 1780599ノート

反応式

HRID 1780599 の反応式
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[OH:10].[C:11](=O)([O-])[O-].[K+].[K+].[CH3:17][C:18]([CH3:20])=O>>[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[O:10][CH2:17][C:18](=[CH2:20])[CH3:11]

参加物

4

反応物 3

HCID 180AcetoneHCID 11430Potassium CarbonateHCID 127692,3,5-Trimethylphenol

生成物 1

HCID 11830229Benzene, 1,2,5-trimethyl-3-[(2-methyl-2-propenyl)oxy]-収率 75%

実験手順

To a solution of 100 g of 2,3,5-trimethylphenol in 500 ml of acetone was added 75 g of anhydrous potassium carbonate. After refluxing for 45 hours, the reaction mixture was filtered, concentrated under reduced pressure and diluted with diethyl ether. The mixture was extracted three times with 300 ml of 20% aqueous solution of sodium hydroxide. The combined organic extracts were washed with water, dried over anhydrous magnesium sulfate, filtered and concentrated under the reduced pressure to afford the compound of methallyl 2,3,5-trimethylphenyl ether(105 g, yield 75%) as colorless liquid.

後処理

  1. temperatureAfter refluxing for 45 hours
  2. filtrationthe reaction mixture was filtered
  3. concentrationconcentrated under reduced pressure
  4. additiondiluted with diethyl ether
  5. extractionThe mixture was extracted three times with 300 ml of 20% aqueous solution of sodium hydroxide
  6. washThe combined organic extracts were washed with water
  7. dry with materialdried over anhydrous magnesium sulfate
  8. filtrationfiltered
  9. concentrationconcentrated under the reduced pressure

出典と根拠

ORDレコード
ord-f9193d2ce6844b489ec729db168068b3
出典データセット
uspto-grants-1997_05
特許番号
US05631208

反応ノート

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