N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine → 5-(3,4-Dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole

関与物質

反応手順

2.0 g of N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy] acetamidine are held at reflux temperature for 1 hour in 20 ml of glacial acetic acid. After distillation of the acetic acid, the crystalline residue is recrystallized from ether/hexane. There is obtained 5-(3,4-dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole in the form of colorless crystals of m.p. 111°.

情報源と証拠