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Lithium Hydroxide → (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Lithium Hydroxide | HCID 3939 | — |
| 反応物 | (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester | HCID 59639322 | — |
| 生成物 | (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid | HCID 10059030 | 46% |
反応手順
This reaction was performed as previously described by Deechongkit, S.; You, S.-L.; Kelly, J. W. Org. Lett. 2004, 6, 497, using (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester 110b and lithium hydroxide. (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid 110c (3.08 g, 14.51 mmol, 46%) was isolated as a viscous oil: MS calcd. for C10H12O3S (M+Na+) 235.1, found 235.3.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07501408B2 |
| 出典データセット | uspto-grants-2009_03 |
| ORD ID | ord-da02151b449d42cbbe103aa172662fa2 |
| 出典メモ | uspto-grants-2009_03 |