関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethylorthoformate | HCID 53630039 | — |
| 反応物 | 2-Cyclopropylamino-5-nitrobenzenesulphonamide | HCID 67530158 | — |
| 生成物 | 4-cyclopropyl-7-nitro-4H-1,2,4-benzothiadiazine 1,1-dioxide | HCID 67530771 | — |
反応手順
In a round-bottom flask, a mixture of 2-cyclopropylamino-5-nitrobenzenesulphonamide (5 g), originating from the Step above, and ethyl orthoformate (50 mL) is heated in the open state at 130° C. for 3 hours. The suspension obtained is cooled on an ice bath and the insoluble material is collected by filtration, washed with ether and dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07741320B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-d3c399511b97447abf51faf290d79fe9 |
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| 出典メモ | uspto-grants-2010_06 |
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