戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 1784073作成日：2026年10月25日

2-Amino-m-cresol → 2-(2-Hydroxy-6-methyl-phenylamino)-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one

https://huagongshe.com/reaction/1784073

反応式

関与物質

役割名称HCID仕込み量
反応物2-Amino-m-cresolHCID 3014138—
反応物2-chloro-9-methoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-oneHCID 57591093—
生成物2-(2-Hydroxy-6-methyl-phenylamino)-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-oneHCID 57591097—

反応手順

The title compound was prepared from 2-chloro-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one (4) and 2-hydroxy-6-methyl-aniline as in Example 1 d. 1H-NMR (400 MHz, d6-DMSO, at 60° C.) δ 9.39 (br, 1H), 8.60 (br, 1H), 7.61 (br, 1H), 7.05-6.95 (3H), 6.75 (d, 1H), 6.73 (d, 1H), 6.34 (br, 1H), 3.95 (t, 2H), 3.83 (s, 3H), 2.95 (t, 2H), and 2.19 (s, 3H); MS (ESI) (M+H)+ 350.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07501512B2
出典データセットuspto-grants-2009_03
ORD IDord-1213ad2a0e2b4298960163ed0da23b17
出典メモuspto-grants-2009_03