化工社化工社 化学情報印刷レポート · 研究参考用
2-Amino-5-chlorobenzenesulphonamide → 7-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-5-chlorobenzenesulphonamide | HCID 12295550 | — |
| 反応物 | Ethylorthoformate | HCID 53630039 | — |
| 生成物 | 7-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide | HCID 10036276 | — |
反応手順
A mixture of 2-amino-5-chlorobenzenesulphonamide (obtained according to J. Chem. Soc. Perkin I, 1043-1047, 1979) and ethyl orthoformate (40 mL) is heated at boiling for 30 minutes in an open vessel. The volume of the mixture is reduced by half under reduced pressure. The precipitate obtained is collected by filtration, washed with ether and dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741320B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-6b717345c1614eb9a2a1a77154c00af2 |
| 出典メモ | uspto-grants-2010_06 |