Malononitrile → N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

HRID 1784915

反応式

HRID 1784915 の反応式
[NH:1]([C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].[C:13](#[N:17])[CH2:14][C:15]#[N:16]>C(O)C.N1CCCCC1>[C:15]([C:14]([C:13]#[N:17])=[CH:9][C:8]1[CH:11]=[CH:12][C:5]([NH:1][C:2](=[O:3])[CH3:4])=[CH:6][CH:7]=1)#[N:16]

参加物

5

反応物 2

HCID 8010MalononitrileHCID 739424-Acetamidobenzaldehyde

生成物 1

HCID 33296N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

試薬・触媒・溶媒 2

HCID 8082Piperidine触媒HCID 702Ethanol溶媒

実験手順

32.6 g (0.2 mol) of 4-acetaminobenzaldehyde and 13.74 g (0.208 mol) of malononitrile are initially charged in 140 ml of ethanol, and 24 drops of piperidine are added. The mixture is stirred at reflux for 30 min. After cooling, the crystals are filtered off with suction and dried.

後処理

  1. temperatureat reflux for 30 min
  2. temperatureAfter cooling
  3. filtrationthe crystals are filtered off with suction
  4. customdried

出典と根拠

ORDレコード
ord-f87e5dfbcd364d2c8293d075f4d09f50
出典データセット
uspto-grants-2009_03
特許番号
US07504421B2

関連ノート

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