HCID 67228996、化合物 → HCID 67229659、化合物
反応式
C(OC(=O)[NH:10][C:11]1[C:20]2[CH2:19][CH:18]([NH:21][S:22]([CH3:25])(=[O:24])=[O:23])[CH2:17][CH2:16][C:15]=2[CH:14]=[CH:13][CH:12]=1)C1C=CC=CC=1>CO.C(Cl)Cl>[NH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[C:15]2[C:20]=1[CH2:19][CH:18]([NH:21][S:22]([CH3:25])(=[O:24])=[O:23])[CH2:17][CH2:16]2参加物
3
実験手順
The title compound was prepared using the procedure as described in Example 20E substituting the product of Example 23A (280 mg, 0.748 mmol) for the product Example 20D. Flash chromatography (5% to 10% CH3OH/CH2Cl2) gave 129 mg (72%) of the title compound as a white solid. 1H NMR (DMSO-d6) δ 7.20 (d, J=7.5 Hz, 1H), 6.79 (t, J=7.8 Hz, 1H), 6.43 (m, 1H), 6.30 (m, 1H), 4.74 (s, 2H), 3.55 (m, 1H), 2.99 (s, 3H), 2.75 (m, 3H), 2.22 (m, 1H), 1.95 (m, 1H), 1.58 (m, 1H); MS (DCI+) m/z 241 (M+H)+.
後処理
- customThe title compound was prepared