Hydrazine → HCID 178446164、化合物
反応式
[CH2:1]([N:6]1[C:14]2[N:13]=[CH:12][NH:11][C:10]=2[C:9](=[O:15])[NH:8][C:7]1=S)[CH2:2][CH2:3][CH2:4][CH3:5].[NH2:17][NH2:18]>O>[CH2:1]([N:6]1[C:14]2[N:13]=[CH:12][NH:11][C:10]=2[C:9](=[O:15])[NH:8]/[C:7]/1=[N:17]\[NH2:18])[CH2:2][CH2:3][CH2:4][CH3:5]参加物
4
反応条件
- 温度
- 100 °C
実験手順
3-Pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one (6.0 g, 16 mmol) was mixed with hydrazine (10 mL, 300 mmol) and water (10 mL). The mixture was heated at 100° C. for 8 h. The solid formed was filtered and washed with water to give the desired product (3.0 g, 78%). LCMS calculated for C10H17N6O (M+H): 237.1; found: 237.1.
後処理
- customThe solid formed
- filtrationwas filtered
- washwashed with water
出典と根拠
- ORDレコード
- ord-c5affaf43c70471d821746c1e957c5ee
- 出典データセット
- uspto-grants-2009_03
- 特許番号
- US07511050B2
反応ノート
読み込み中…