Linoleoyl chloride → (7Z,10Z)-hexadeca-7,10-dienoic anhydride

HRID 1788309

反応式

HRID 1788309 の反応式
[C:1](Cl)(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11]/[CH:12]=[CH:13]\[CH2:14][CH2:15][CH2:16]CC.N[CH:22]([CH3:26])[C:23]([O-:25])=[O:24].[NH4+]>>[C:23]([O:25][C:1](=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]/[CH:7]=[CH:8]\[CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])(=[O:24])[CH2:22][CH2:26][CH2:13][CH2:12][CH2:11]/[CH:10]=[CH:9]\[CH2:8]/[CH:7]=[CH:6]\[CH2:5][CH2:4][CH2:3][CH2:2][CH3:1]

参加物

3

反応物 2

HCID 9817754Linoleoyl chloride2 回HCID 86624725HCID 86624725、化合物

生成物 1

HCID 86624724(7Z,10Z)-hexadeca-7,10-dienoic anhydride

実験手順

Finally, in a dry 2-necked, round bottomed flask, fixed with a separatory funnel, containing 17.93 g (60 mmol) of the prepared (9Z,12Z)-octadeca-9,12-dienoyl chloride, and side arm water condenser fixed with a dry receiving flask, is placed 7.64 g (72 mmol) of ammonium 2-aminopropanoate. The round bottomed flask is placed in an ice bath and the (9Z,12Z)-octadeca-9,12-dienoyl chloride is added drop wise. After addition is completed the mixture is shaken and the ice bath is replaced by a heating mantle. The flask is then heated until no more solution is dropping into the receiving flask. This crude distillate is then further fractionally distilled to yield 2-aminopropanoic (7Z,10Z)-hexadeca-7,10-dienoic anhydride.

後処理

  1. customFinally, in a dry 2-necked, round bottomed flask, fixed with a separatory funnel
  2. customThe round bottomed flask is placed in an ice bath
  3. additionAfter addition
  4. temperatureThe flask is then heated until no more solution
  5. distillationThis crude distillate is then further fractionally distilled

出典と根拠

ORDレコード
ord-a4c3049184d5482a8a34391cdcb4880c
出典データセット
uspto-grants-2009_03
特許番号
US07511162B2

関連ノート

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