1-Dodecanol → n-Dodecyl 2-[4-(5-Trifluoromethyl-2-Pyridinyloxy) Phenoxy]Propanoate

HRID 1788860ノート

反応式

HRID 1788860 の反応式
[CH2:1]([OH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[F:21][C:22]([F:43])([F:42])[C:23]1[CH:24]=[CH:25][C:26]([O:29][C:30]2[CH:41]=[CH:40][C:33]([O:34][CH:35]([CH3:39])[C:36](Cl)=[O:37])=[CH:32][CH:31]=2)=[N:27][CH:28]=1>C1(C)C=CC=CC=1>[F:42][C:22]([F:21])([F:43])[C:23]1[CH:24]=[CH:25][C:26]([O:29][C:30]2[CH:41]=[CH:40][C:33]([O:34][CH:35]([CH3:39])[C:36]([O:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:37])=[CH:32][CH:31]=2)=[N:27][CH:28]=1

参加物

5

反応物 3

HCID 81931-DodecanolHCID 8471TriethylamineHCID 130552202-(4-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoyl chloride

生成物 1

HCID 20189152n-Dodecyl 2-[4-(5-Trifluoromethyl-2-Pyridinyloxy) Phenoxy]Propanoate

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒2 回

反応条件

温度
10 °C

実験手順

n-Dodecanol(2.5 grams; 0.134mol), toluene (80 ml) and triethylamine (5 ml) were placed into a 300 ml, 3-necked glass reaction flask equipped with stirrer, thermometer, reflux condenser, and nitrogen line. 2-[4-(5-trifluoromethyl-2-pyridinyloxy)phenoxy]propanoic acid chloride (4.45 grams; 0.0125 mol) in toluene (30 ml) was added dropwise to the reaction mixture with stirring at a temperature of about 10° C. The temperature of the reaction mixture was allowed to rise to room temperature and stirred overnight.

後処理

  1. customequipped with stirrer
  2. temperaturethermometer, reflux condenser
  3. customto rise to room temperature
  4. stirringstirred overnight

出典と根拠

ORDレコード
ord-43deab324a3240d394a7343e641e646e
出典データセット
uspto-grants-1987_08
特許番号
US04685960

反応ノート

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