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2-Trifluoromethylbenzenesulphonyl chloride → 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Trifluoromethylbenzenesulphonyl chloride | HCID 136616 | — |
| 反応物 | 1,4-Naphthalenedione, 2-chloro-3-(1-piperazinyl)- | HCID 699794 | — |
| 生成物 | 1-(3-Chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-4-[[2-(trifluoromethyl)phenyl]sulfonyl]piperazine | HCID 13934779 | — |
反応手順
A 1.5 g portion of 3-chloro-2-piperazinyl-1,4-naphthoquinone and 1.26 g of 2-trifluoromethylbenzenesulfonyl chloride were reacted as described in Example 56, giving 1.53 g of the desired product, mp 122°-124° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04686220 |
| 出典データセット | uspto-grants-1987_08 |
| ORD ID | ord-e28d3533b1644cf894614640d3f6f843 |
| 出典メモ | uspto-grants-1987_08 |