HCID 13912877、化合物 → HCID 20189753、化合物

HRID 1789081ノート

反応式

HRID 1789081 の反応式
[CH3:1][N:2]([CH3:17])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([N+:11]([O-])=O)=[CH:6][C:5]=1[O:14][CH3:15]>C(O)C.[C].[Pd]>[CH3:17][N:2]([CH3:1])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([NH2:11])=[CH:6][C:5]=1[O:14][CH3:15]

参加物

4

反応物 1

HCID 13912877HCID 13912877、化合物

生成物 1

HCID 20189753HCID 20189753、化合物

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

A suspension of 3.62 g of N,N-dimethyl 5-amino-2-methoxy4-nitrobenzamide and 150 mg of 10 % palladium carbon in 140 ml of ethanol was stirred at 70°-80° C. under a hydrogen atmosphere. After the absorption of hydrogen was completed, the catalyst was removed by filtration, and the filtrate was evaporated to dryness to give crude N,N-dimethyl 4,5-diamino2-methoxybenzamide, which was then dissolved in 30 ml of tetrahydrofuran.

後処理

  1. customAfter the absorption of hydrogen
  2. customthe catalyst was removed by filtration
  3. customthe filtrate was evaporated to dryness

出典と根拠

ORDレコード
ord-25d717c20516453d9c35a1cb80195294
出典データセット
uspto-grants-1987_08
特許番号
US04686292

反応ノート

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