Glyceraldehyde → Benzyl 4,5-dihydroxy-2-pentenoate

HRID 1790815

反応式

HRID 1790815 の反応式
[CH2:1]([OH:6])[CH:2]([OH:5])[CH:3]=O.[Br-].[CH2:8]([O:15][C:16]([CH2:18][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=[O:17])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>O1C(CC)C1>[OH:5][CH:2]([CH2:1][OH:6])[CH:3]=[CH:18][C:16]([O:15][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:17]

参加物

4

反応物 2

HCID 751GlyceraldehydeHCID 11214019(Benzyloxycarbonylmethyl)triphenylphosphonium bromide

生成物 1

HCID 54529065Benzyl 4,5-dihydroxy-2-pentenoate

試薬・触媒・溶媒 1

HCID 78341,2-Epoxybutane溶媒

実験手順

A mixture of DL-glycerinaldehyde (4,5 g, 50 mmole) and (benzyloxycarbonylmethyl)-triphenyl-phosphoniumbromide (24.57 g, 50 mmole) in 100 ml 1,2-epoxybutane was refluxed overnight. The mixture was evaporated under vacuum and the product was isolated by silica gel column chromatography.

後処理

  1. temperaturewas refluxed overnight
  2. customThe mixture was evaporated under vacuum
  3. customthe product was isolated by silica gel column chromatography

出典と根拠

ORDレコード
ord-af17f8c318544e7da024f3bc7e2d6950
出典データセット
uspto-grants-2006_07
特許番号
US07071173B2

関連ノート

読み込み中…