Ethanol → Ethyl (2-methoxyethoxy)acetate

HRID 1792510ノート

反応式

HRID 1792510 の反応式
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][C:7]([OH:9])=[O:8].S(=O)(=O)(O)O.[CH2:15](O)[CH3:16]>>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][C:7]([O:9][CH2:15][CH3:16])=[O:8]

参加物

4

反応物 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 27642(2-Methoxyethoxy)acetic acid

生成物 1

HCID 9898912Ethyl (2-methoxyethoxy)acetate

実験手順

150 mL solution of 10 g (2-methoxyethoxy)acetic acid and 1 mL conc. sulfuric acid in ethanol was heated for 3 hours under reflux, and then the solvent was removed. The resulting residue was diluted with ethyl acetate and washed with an aqueous saturated sodium bicarbonate solution and brine. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was removed, whereby 9.5 g of the title compound (colorless oil) was obtained.

後処理

  1. temperatureunder reflux
  2. customthe solvent was removed
  3. additionThe resulting residue was diluted with ethyl acetate
  4. washwashed with an aqueous saturated sodium bicarbonate solution and brine
  5. dry with materialThe organic layer was dried over anhydrous sodium sulfate
  6. customthe solvent was removed

出典と根拠

ORDレコード
ord-adb0227557f042d48c4b0bb45bdb7e7a
出典データセット
uspto-grants-2006_07
特許番号
US07074801B1

反応ノート

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