2,4-Dichlorobenzylidenemalononitrile → 5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-naphthalen-2-yl-pyrimidin-4-ylamine

HRID 1793914ノート

反応式

HRID 1793914 の反応式
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]([NH2:13])=[NH:12].[Cl:14][C:15]1[CH:26]=[C:25]([Cl:27])[CH:24]=[CH:23][C:16]=1[CH:17]=[C:18]([C:21]#[N:22])[C:19]#[N:20]>>[NH2:22][CH2:21][C:18]1[C:19]([NH2:20])=[N:12][C:11]([C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)=[N:13][C:17]=1[C:16]1[CH:23]=[CH:24][C:25]([Cl:27])=[CH:26][C:15]=1[Cl:14]

参加物

3

反応物 2

HCID 180892,4-DichlorobenzylidenemalononitrileHCID 193409beta-Naphthamidine

生成物 1

HCID 101266375-Aminomethyl-6-(2,4-dichloro-phenyl)-2-naphthalen-2-yl-pyrimidin-4-ylamine

実験手順

The title compound, MS: m/e=394.9 (M+H+), was prepared from naphthalene-2-carboxamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

出典と根拠

ORDレコード
ord-c8aca1cf9e64480b89ac76c1f4691077
出典データセット
uspto-grants-2006_04
特許番号
US07022718B2

反応ノート

読み込み中…