2-Cyclohexylmethyl-4-morpholin-4-yl-4-oxobutyric acid → (R)-2-Cyclohexylmethyl-4-morpholin-4-yl-N-[(S)-1-(oxazole-2-carbonyl)-3-phenyl-propyl]-4-oxo-butyramide
反応式
[NH2:1][CH:2]([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C@@H:3]([C:5]1[O:6][CH:7]=[CH:8][N:9]=1)[OH:4].[CH:18]1([CH2:24][CH:25]([CH2:29][C:30]([N:32]2[CH2:37][CH2:36][O:35][CH2:34][CH2:33]2)=[O:31])[C:26](O)=[O:27])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([CH2:24][C@H:25]([CH2:29][C:30]([N:32]2[CH2:37][CH2:36][O:35][CH2:34][CH2:33]2)=[O:31])[C:26]([NH:1][C@H:2]([C:3]([C:5]2[O:6][CH:7]=[CH:8][N:9]=2)=[O:4])[CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:27])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1参加物
3
実験手順
It is similarly prepared according to the general procedure for example 10 but using (S)-2-Amino-1-oxazol-2-yl-4-phenyl-butan-1-ol and 2-Cyclohexylmethyl-4-morpholin-4-yl-4-oxo-butyric acid.
後処理
- customIt is similarly prepared