Methylamine → 1,5-Dimethylpyrrolidin-2-one

HRID 1796695

反応式

HRID 1796695 の反応式
[CH3:1][C:2]1[O:7][C:5](=[O:6])[CH2:4][CH:3]=1.[CH3:8][NH2:9]>>[CH2:1]=[C:2]1[N:9]([CH3:8])[C:5](=[O:7])[CH2:4][CH2:3]1.[CH3:8][N:9]1[CH:2]([CH3:1])[CH2:3][CH2:4][C:5]1=[O:6]

参加物

4

反応物 2

HCID 6329MethylamineHCID 11559alpha-Angelica lactone

生成物 2

HCID 1011941,5-Dimethylpyrrolidin-2-oneHCID 13462148HCID 13462148、化合物

実験手順

Wedler, et al. (Journal. f. prakt. Chemie (1990) 332:557–562) discuss a process for producing 5-hydroxy-1,5-dimethyl-2-pyrrolidone by reacting α-angelica lactone with methylamine. Dehydration of this product resulted in the formation of the unstable 5-methylene-N-methyl-2-pyrrolidone, rather than the desired 1,5-dimethyl-2-pyrrolidone.

出典と根拠

ORDレコード
ord-1045b4d2557a44dbbd01acf61a1aed1c
出典データセット
uspto-grants-2006_04
特許番号
US07030249B2

関連ノート

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