N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide → 1-(5-(3,5-Dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone
反応式
CON(C)[C:4](=[O:20])[CH:5]([O:18][CH3:19])[C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[CH:8][CH:7]=1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([C:32]2[O:33][CH:34]=[CH:35][CH:36]=2)[CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1>>[CH3:22][O:23][C:24]1[CH:25]=[C:26]([C:32]2[O:33][C:34]([C:4](=[O:20])[CH:5]([O:18][CH3:19])[C:6]3[CH:7]=[CH:8][C:9]([N:12]4[CH2:13][CH2:14][O:15][CH2:16][CH2:17]4)=[CH:10][CH:11]=3)=[CH:35][CH:36]=2)[CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1参加物
3
実験手順
N,2-Dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide was coupled with 2-(3,5-dimethoxyphenyl)furan following the procedure of Example 12. 1-(5-(3,5-Dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone was isolated as a yellow oily foam (0.343 g, 62% yield). MS: m/z 438.2 [M+H]+.
出典と根拠
- ORDレコード
- ord-e37490adb30c4206bc70ccb65406c850
- 出典データセット
- uspto-grants-2013_01