Methylparaben → N-{4-[2-(4-Methoxyphenyl)ethoxy]benzoyl}glycine

HRID 1799242

反応式

HRID 1799242 の反応式
[CH:1]1([CH2:4][CH2:5][O:6][C:7]2[CH:19]=[CH:18][C:10]([C:11]([NH:13][CH2:14][C:15]([OH:17])=[O:16])=[O:12])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.OC1C=C[C:24]([C:25]([O:27][CH3:28])=O)=[CH:23]C=1.COC1C=CC(CCO)=CC=1>>[CH3:28][O:27][C:25]1[CH:2]=[CH:3][C:1]([CH2:4][CH2:5][O:6][C:7]2[CH:8]=[CH:9][C:10]([C:11]([NH:13][CH2:14][C:15]([OH:17])=[O:16])=[O:12])=[CH:18][CH:19]=2)=[CH:23][CH:24]=1

参加物

4

反応物 3

HCID 7456MethylparabenHCID 697054-Methoxyphenethyl alcoholHCID 66812105N-[4-(2-Cyclopropylethoxy)benzoyl]glycine

生成物 1

HCID 66812093N-{4-[2-(4-Methoxyphenyl)ethoxy]benzoyl}glycine収率 79%

実験手順

Reactions similar to those described in Example 1 (1a) and (1b) were conducted using methyl 4-hydroxybenzoate (4.56 g, 30.0 mmol) and 2-(4-methoxyphenyl)ethanol (5.03 g, 33.0 mmol) to give 7.80 g of the title compound (white powder, yield: 79%).

出典と根拠

ORDレコード
ord-5190dba4f85c4f16bff6c6b983662061
出典データセット
uspto-grants-2013_01
特許番号
US08344029B2

関連ノート

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