Methylparaben → Benzoic acid, 4-[(2E)-2-buten-1-yloxy]-

反応式

[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8]C)=[O:7])=[CH:4][CH:3]=1.[CH2:12](O)/[CH:13]=[CH:14]/[CH3:15]>>[CH2:12]([O:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)/[CH:13]=[CH:14]/[CH3:15]

参加物

反応物 2

HCID 7456Methylparaben

HCID 637922trans-Crotyl alcohol

生成物 1

HCID 23321309Benzoic acid, 4-[(2E)-2-buten-1-yloxy]-収率 91.4%

実験手順

A reaction similar to that described in Example 1 (1a) was conducted using methyl 4-hydroxybenzoate (5.00 g, 32.9 mmol) and trans-crotyl alcohol (manufactured by Fluka, 2.37 g, 32.9 mmol) to give 5.78 g of the title compound (white powder, yield: 91%).

後処理

customA reaction similar to

出典と根拠

ORDレコード: ord-414aabce67944881819f211b8a8ecff2
出典データセット: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08344029B2

反応ノート

読み込み中…