化工社化工社 化学情報印刷レポート · 研究参考用
4-(3,3,3-Trifluoropropoxy)benzoic acid → 2-[((2S)-3-[4-(Trifluoromethoxy)phenyl]-2-{[4-(3,3,3-trifluoropropoxy)benzoyl]amino}propanoyl)amino]ethyl acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(3,3,3-Trifluoropropoxy)benzoic acid | HCID 58111655 | — |
| 反応物 | 2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetate | HCID 69017543 | — |
| 生成物 | 2-[((2S)-3-[4-(Trifluoromethoxy)phenyl]-2-{[4-(3,3,3-trifluoropropoxy)benzoyl]amino}propanoyl)amino]ethyl acetate | HCID 86636528 | — |
反応手順
A reaction similar to that described in Example 50 was conducted using 2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetate and 4-(3,3,3-trifluoropropoxy)benzoic acid obtained in the preparation process of Example 33 (33a) to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08344029B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-51dd829be42c434d97bbd61c8335b8b7 |
| 出典メモ | uspto-grants-2013_01 |