3-(Pyrrolidin-1-yl)aniline → 2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(pyrrolidin-1-yl)phenylamino)pyrimidine-5-carboxamide
反応式
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13](NC2C=CC(C3ON=CC=3)=CC=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[N:30]1([C:35]2[CH:36]=[C:37]([CH:39]=[CH:40][CH:41]=2)[NH2:38])[CH2:34][CH2:33][CH2:32][CH2:31]1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:38][C:37]2[CH:39]=[CH:40][CH:41]=[C:35]([N:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[CH:36]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1参加物
3
実験手順
This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-(pyrrolidin-1-yl)aniline in step 1. MS: 396.6 (M+H).
後処理
- customThis compound was synthesised