化工社化工社 化学情報印刷レポート · 研究参考用
(R)-4-Methyloxazolidin-2-one → methyl (R)-3-fluoro-4-(4-methyl-2-oxooxazolidin-3-yl)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-4-Methyloxazolidin-2-one | HCID 2734858 | — |
| 反応物 | Methyl 4-bromo-3-fluorobenzoate | HCID 21951878 | — |
| 生成物 | methyl (R)-3-fluoro-4-(4-methyl-2-oxooxazolidin-3-yl)benzoate | HCID 58484559 | 92% |
反応手順
By reaction and treatment in the same manner as in Preparation Example 12 and using methyl 4-bromo-3-fluorobenzoate (1.2 g) and (R)-4-methyloxazolidin-2-one (607 mg) described in Preparation Example 25, the title compound (1.2 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354401B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-dcd11aec23964959813ce4c5b17fd4e6 |
| 出典メモ | uspto-grants-2013_01 |