化工社化工社 化学情報印刷レポート · 研究参考用
4-Bromo-2-fluorobenzoyl chloride → (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-2-fluorobenzoyl chloride | HCID 2734026 | — |
| 反応物 | (3,5-Dimethylpyrazin-2-yl)piperazine hydrochloride | HCID 67381341 | — |
| 生成物 | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone | HCID 58484696 | 69.9% |
反応手順
By reaction and treatment in the same manner as in Preparation Example 8 and using 4-bromo-2-fluorobenzoyl chloride (1.1 g) and 1-(3,5-dimethylpyrazin-2-yl)piperazine hydrochloride (915 mg) described in Preparation Example 59, the title compound (1.1 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354401B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-4cd6e7e1f65a44afb88ec664acedf589 |
| 出典メモ | uspto-grants-2013_01 |