1-(5-Bromo-3-methylpyridin-2-yl)piperazine → HCID 58484740、化合物
反応式
[F:1][C:2]1[CH:10]=[C:9]([CH3:11])[C:5]([C:6]([OH:8])=O)=[CH:4][N:3]=1.[Br:12][C:13]1[CH:14]=[C:15]([CH3:25])[C:16]([N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)=[N:17][CH:18]=1>>[Br:12][C:13]1[CH:14]=[C:15]([CH3:25])[C:16]([N:19]2[CH2:20][CH2:21][N:22]([C:6]([C:5]3[CH:4]=[N:3][C:2]([F:1])=[CH:10][C:9]=3[CH3:11])=[O:8])[CH2:23][CH2:24]2)=[N:17][CH:18]=1参加物
3
実験手順
By reaction and treatment in the same manner as in Preparation Example 69 and using 6-fluoro-4-methylnicotinic acid (931 mg) and 1-(5-bromo-3-methylpyridin-2-yl)piperazine (1.5 g), the title compound (1 g) was obtained.
後処理
- customBy reaction and treatment in the same manner
- customas in Preparation Example 69
出典と根拠
- ORDレコード
- ord-125e8a21052c4df7ad44c96b6a00f346
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08354401B2
反応ノート
読み込み中…