化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 3-(Propan-2-yl)benzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 1-Bromo-3-isopropylbenzene | HCID 138499 | — |
| 反応物 | HCID 178418260 | HCID 178418260 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 3-(Propan-2-yl)benzonitrile | HCID 258440 | — |
反応手順
5.15 g (25.87 mmol) m-bromo-isopropyl-benzene and 2.69 g (30.04 mmol) copper cyanide are stirred in 2.50 ml of pyridine for 24 hours at 180° C. Then 15 ml of water, 15 ml of toluene and 15 ml conc. ammonia solution are added, then the mixture is extracted. The organic phase is dried and evaporated to dryness.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08354418B2 |
| 出典データセット | uspto-grants-2013_01 |
| ORD ID | ord-656f53ae722d463c8e6a0eff14f36527 |
| 出典メモ | uspto-grants-2013_01 |