2-Chloroethyl isocyanate → HCID 11736224、化合物
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[Cl:10][CH2:11][CH2:12][N:13]=[C:14]=[O:15]>O1CCOCC1>[Cl:10][CH2:11][CH2:12][NH:13][C:14]([NH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:4]([C:5]#[N:6])[CH:3]=1)=[O:15]参加物
4
反応条件
- 温度
- 60 °C
実験手順
65.00 g (550 mmol) 3-amino-benzonitrile are dissolved in 450 ml dioxane, 56 ml (660 mmol) 1-chloro-2-isocyanato-ethane dissolved in 60 ml dioxane are added dropwise. The reaction mixture is stirred for 3 hours at 60° C. and for 16 hours at ambient temperature. Then the precipitate is suction filtered, washed with diethyl ether and dried.
後処理
- additionare added dropwise
- filtrationfiltered
- washwashed with diethyl ether
- customdried
出典と根拠
- ORDレコード
- ord-f178c7818a4e47e1b16e7bdda00327cf
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08354418B2
反応ノート
読み込み中…