Potassium Hydroxide → 3-(2-Oxoimidazolidin-1-yl)benzonitrile
反応式
Cl[CH2:2][CH2:3][NH:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14]#[N:15])[CH:9]=1)=[O:6].[OH-].[K+]>C(O)C>[O:6]=[C:5]1[NH:4][CH2:3][CH2:2][N:7]1[C:8]1[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=1)[C:14]#[N:15]参加物
4
実験手順
110.00 g (490 mmol) 1-(2-chloro-ethyl)-3-(3-cyano-phenyl)-urea are dissolved in 2000 ml of ethanol at 50° C. and a solution of 42.00 g (640 mmol) potassium hydroxide in 390 ml of ethanol is added within 1.5 hours. The reaction mixture is stirred for 16 hours at ambient temperature, then the precipitate formed is suction filtered, washed with water and dried.
後処理
- customthe precipitate formed
- filtrationfiltered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-11c7c62c2f054b609d970bfa20080a3c
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08354418B2
反応ノート
読み込み中…