3-(Dimethylaminomethyl)benzonitrile → 1-(3-(Aminomethyl)phenyl)-N,N-dimethylmethanamine
反応式
[CH3:1][N:2]([CH2:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[C:8]#[N:9])[CH3:3]>N.[Ni]>[CH3:3][N:2]([CH2:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH2:8][NH2:9])[CH3:1]参加物
4
実験手順
7.00 g (34.95 mmol) 3-dimethylaminomethyl-benzonitrile are placed in 100 ml of methanolic ammonia solution and hydrogenated with 1.40 g Raney nickel at ambient temperature under a pressure of 3 bar. The catalyst is suction filtered, the filtrate is evaporated down. The residue is purified by chromatography.
後処理
- filtrationfiltered
- customthe filtrate is evaporated down
- customThe residue is purified by chromatography
出典と根拠
- ORDレコード
- ord-cc3e026be93e4d69bbb85eddd8afeb61
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08354418B2
反応ノート
読み込み中…