Ethyl pyruvate → Ethyl pyruvate 3-nitrophenylhydrazone

HRID 1804901

反応式

HRID 1804901 の反応式
Cl.[N+:2]([C:5]1[CH:6]=[C:7]([NH:11][NH2:12])[CH:8]=[CH:9][CH:10]=1)([O-:4])=[O:3].[CH2:13]([O:15][C:16](=[O:20])[C:17](=O)[CH3:18])[CH3:14]>C(O)C>[CH2:13]([O:15][C:16](=[O:20])[C:17](=[N:12][NH:11][C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([N+:2]([O-:4])=[O:3])[CH:6]=1)[CH3:18])[CH3:14]

参加物

4

反応物 2

HCID 12041Ethyl pyruvateHCID 54642853-Nitrophenylhydrazinium(1+) chloride

生成物 1

HCID 255590Ethyl pyruvate 3-nitrophenylhydrazone

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

(3-Nitro-phenyl)-hydrazine hydrochloride salt (B-4-a) (30.2 g, 0.16 mol) and 2-oxo-propionic acid ethyl ester (22.3 g, 0.19 mol) was dissolved in ethanol (300 mL). The mixture was stirred at room temperature for 4 h. The solvent was evaporated under reduced pressure to give 2-[(3-nitro-phenyl)-hydrazono]-propionic acid ethyl ester, which was used directly in the next step.

後処理

  1. customThe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-f0aadff933264e06898b74c375a2d48b
出典データセット
uspto-grants-2013_01
特許番号
US08354427B2

関連ノート

読み込み中…