Potassium Cyanide → 4-Chloro-2-methylbenzeneacetonitrile
反応式
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Cl)=[C:4]([CH3:10])[CH:3]=1.[C-:11]#[N:12].[K+]>C(O)C.O>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][C:11]#[N:12])=[C:4]([CH3:10])[CH:3]=1参加物
5
実験手順
Step B In a manner similar to the method described in Example 57 Step B, 4-chloro-2-methylbenzyl chloride (1.83 g, 10 mmol) was reacted with KCN (1.76 g, 27 mmol) in ethanol (13 mL) and water (10 mL) at 100° C. for 1 h to give 4-chloro-2-methylbenzyl cyanide as a yellow oil (1.2 g, 69%)
出典と根拠
- ORDレコード
- ord-0285d8a9d5ba420bb55abaaaa371b96e
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08354444B2
反応ノート
読み込み中…